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Biosynthesis of silver nanoparticles using Dittrichia graveolens (Asteraceae) leaves extract: characterisation and assessment of their antioxidant activity

Yıl 2022, Cilt 5, Sayı 1, 50 - 56, 31.03.2022
https://doi.org/10.38059/biodiversity.1090549

Öz

Nanotechnology has gained great interest recently due to its common applications. Synthesis of silver nanoparticles employing medicinal plants is eco-friendly, low cost, and easy. Silver nanoparticles (i-AgNPs) were synthesized using Dittrichia graveolens leaves extract. The structure of i-AgNPs was identified by extensive spectroscopic studies. The antioxidant effect of extract and i-AgNPs was determined by DPPH•, ABTS•+, and FRAP assays. FTIR spectroscopic study displayed the characteristic vibration of the hydroxyl group at 3262 cm-1. Ultraviolet-Visible (UV-Vis) spectrophotometer exhibited the maximum absorption of i-AgNPs at 451 nm. The particle size of the green synthesized nanostructure was determined as 30.7 nm by scanning electron microscope (SEM). The crystal structure of nanoparticles was established as face-centered cubic (fcc) by X-Ray Diffraction (XRD). DPPH activity of i-AgNPs (13.4±0.34 µg/mL, IC50) was found higher than that of the extract (15.4±0.17 µg/mL, IC50). Dittrichia graveolens contains the bioactive compounds that bring out its reducing and stabilizing properties. The extract and i-AgNPs displayed the promising antioxidant effect that may be a raw material for food and pharmaceutical applications.

Kaynakça

  • Abdel-Aziz MS, Shaheen MS, El-Nekeety AA, Abdel-Wahhab MA (2014). Antioxidant and antibacterial activity of silver nanoparticles biosynthesized using Chenopodium murale leaf extract. Journal of Saudi Chemical Society 18(4): 356-363. https://doi.org/10.1016/j.jscs.2013.09.011
  • Akalın E, Gürdal B, Olcay B (2020). General overview on the conservation of medicinal plants in Turkey. Turkish Journal of Biodiversity 3(2): 86-94. https://doi.org/10.38059/biodiversity.726745
  • Akintelu SA, Olugbeko SC, Folorunso AS (2020). A review on synthesis, optimization, characterization and antibacterial application of gold nanoparticles synthesized from plants. International Nano Letters 10(4): 237-248. https://doi.org/10.1007/s40089-020-00317-7
  • Asad M, Khan A, Jahan B (2020). Variation in biomass production of sunflower (Helianthus annuus) plants under the influence of lemongrass (Cymbopogon erectus) extract. Turkish Journal of Biodiversity 3(2): 69-75. https://doi.org/10.38059/biodiversity.729081
  • Bordoloi M, Sahoo RK, Tamuli KJ, Saikia S, Dutta PP (2020). Plant Extracts Promoted Preparation of Silver and Gold Nanoparticles: A Systematic Review. Nano 15(02): 2030001. https://doi.org/10.1142/S1793292020300017
  • Burlacu E, Tanase C, Coman N-A, Berta L (2019). A review of bark-extract-mediated green synthesis of metallic nanoparticles and their applications. Molecules 24(23): 4354. https://doi.org/10.3390/molecules24234354
  • Dede E, Genc N, Elmastas M, Aksit H, Erenler R (2019). Chemical constituents isolated from Rhododendron ungernii with antioxidant profile. The Natural Products Journal 9(3): 238-243. https://doi.org/10.2174/2210315508666181024114812
  • Elmastas M, Celik SM, Genc N, Aksit H, Erenler R, Gulcin İ (2018). Antioxidant activity of an anatolian herbal tea—Origanum minutiflorum: isolation and characterization of its secondary metabolites. International Journal of Food Properties 21(1): 374-384. https://doi.org/10.1080/10942912.2017.1416399
  • Elmastas M, Telci İ, Akşit H, Erenler R (2015). Comparison of total phenolic contents and antioxidant capacities in mint genotypes used as spices. Turkish Journal of Biochemistry 40(6): 456-462. https://doi.org/10.1515/tjb-2015-0034
  • Emi̇nagaoglu O, Ozcan M, BAK FE, Yüksel E, Beğen HA (2020). Morphological, anatomical and micromorphological characterization of Rhamnus microcarpa (Rhamnaceae). Turkish Journal of Biodiversity 3(1): 1-8. https://doi.org/10.38059/biodiversity.620587
  • Erenler R, Adak T, Karan T, Elmastas M, Yildiz I, Aksit H, Topcu G, Sanda MA (2017a). Chemical constituents isolated from Origanum solymicum with antioxidant activities. The Eurasia Proceedings of Science Technology Engineering and Mathematics 1: 139-145.
  • Erenler R, Dag B (2021). Biosynthesis of silver nanoparticles using Origanum majorana L. and evaluation of their antioxidant activity. Inorganic and Nano-Metal Chemistry 52(4): 485.492. https://doi.org/10.1080/24701556.2021.1952263
  • Erenler R, Meral B, Sen O, Elmastas M, Aydin A, Eminagaoglu O, Topcu G (2017b). Bioassay-guided isolation, identification of compounds from Origanum rotundifolium and investigation of their antiproliferative and antioxidant activities. Pharmaceutical Biology 55(1): 1646-1653. https://doi.org/10.1080/13880209.2017.1310906
  • Erenler R, Nusret G, Elmastaş M, Eminagaoglu O (2019). Evaluation of antioxidant capacity with total phenolic content of Galanthus krasnovii (Amaryllidaceae). Turkish Journal of Biodiversity 2(1): 13-17 https://doi.org/10.38059/biodiversity.526833
  • Erenler R, Sen O, Aksit H, Demirtas I, Yaglioglu AS, Elmastas M, Telci I (2016). Isolation and identification of chemical constituents from Origanum majorana and investigation of antiproliferative and antioxidant activities. Journal of the Science of Food and Agriculture 96(3): 822-836. https://doi.org/10.1002/jsfa.7155.
  • Erenler R, Telci I, Ulutas M, Demirtas I, Gul F, Elmastas M, Kayir O (2015). Chemical constituents, quantitative analysis and antioxidant activities of Echinacea purpurea (L.) moench and Echinacea pallida (N utt.) N utt. Journal of Food Biochemistry, 39(5): 622-630. https://doi.org/10.1111/jfbc.12168
  • Erenler R, Yilmaz S, Aksit H, Sen O, Genc N, Elmastas M, Demirtas I (2014). Antioxidant activities of chemical constituents isolated from Echinops orientalis Trauv. Records of Natural Products 8(1): 32-36. Gecer EN, Erenler R, Temiz C, Genc N, Yildiz I (2021). Green synthesis of silver nanoparticles from Echinacea purpurea (L.) Moench with antioxidant profile. Particulate Science and Technology 1-8. https://doi.org/10.1080/02726351.2021.1904309
  • Genc N, Yildiz I, Chaoui R, Erenler R, Temiz C, Elmastas M (2020). Biosynthesis, characterization and antioxidant activity of oleuropein-mediated silver nanoparticles. Inorganic and Nano-Metal Chemistry 51: 411-419. https://doi.org/10.1080/24701556.2020.1792495
  • Genc N, Yildiz I, Karan T, Eminagaoglu O, Erenler R (2019). Antioxidant activity and total phenolic contents of Galanthus woronowii (Amaryllidaceae). Turkish Journal of Biodiversity 2(1): 1-5.
  • Guzel A, Aksit H, Elmastas M, Erenler R (2017). Bioassay-guided isolation and identification of antioxidant flavonoids from Cyclotrichium origanifolium (Labill.) Manden. and Scheng. Pharmacognosy Magazine 13(50): 316-320. https://doi.org/10.4103/0973-1296.204556
  • Karan T, Erenler R, Bozer BM (2022). Synthesis and characterization of silver nanoparticles using curcumin: cytotoxic, apoptotic, and necrotic effects on various cell lines. Zeitschrift für Naturforschung C https://doi.org/10.1515/znc-2021-0298.
  • Kaya G, Karakaya R, Tilgel E, Sandikci M, Yucel E, Cicek G, Kayir O, Aksit H, Telci I, Guzel A, Elmastas M, Erenler R (2014). Essential oil constituents of Thuja orientalis berries. Journal of New Results in Science 7(7): 1-6.
  • Kumari R, Saini AK, Kumar A, Saini RV (2020). Apoptosis induction in lung and prostate cancer cells through silver nanoparticles synthesized from Pinus roxburghii bioactive fraction. Journal of Biological Inorganic Chemistry 25: 23-37. https://doi.org/10.1007/s00775-019-01729-3
  • Lateef A, Ojo SA, Elegbede JA (2016). The emerging roles of arthropods and their metabolites in the green synthesis of metallic nanoparticles. Nanotechnology Reviews 5(6): 601-622. https://doi.org/10.1515/ntrev-2016-0049
  • Mittal AK, Bhaumik J, Kumar S, Banerjee UC (2014). Biosynthesis of silver nanoparticles: elucidation of prospective mechanism and therapeutic potential. Journal of Colloid and Interface Science 415: 39-47. https://doi.org/10.1016/j.jcis.2013.10.018
  • Palasoglu B, Eminagaoglu O (2022). Folk medicines of Beşpare villages (Artvin-Turkey). Turkish Journal of Biodiversity 5(1): 1-16. https://doi.org/10.38059/biodiversity.1052372
  • Sahin Yaglioglu A, Akdulum B, Erenler R, Demirtas I, Telci I, Tekin S (2013). Antiproliferative activity of pentadeca-(8E, 13Z) dien-11-yn-2-one and (E)-1,8-pentadecadiene from Echinacea pallida (N utt.) N utt. roots. Medicinal Chemistry Research 22(6): 2946-2953. https://doi.org/10.1007/s00044-012-0297-2
  • Topcu G, Erenler R, Cakmak O, Johansson CB, Celik C, Chai H-B, Pezzuto JM (1999). Diterpenes from the berries of Juniperus excelsa. Phytochemistry 50(7): 1195-1199. https://doi.org/10.1016/S0031-9422(98)00675-X

Dittrichia graveolens (Asteraceae) yaprakları kullanılarak gümüş nanopartiküllerin biyosentezi: karakterizasyonu, ve antioksidan aktivitelerinin değerlendirilmesi

Yıl 2022, Cilt 5, Sayı 1, 50 - 56, 31.03.2022
https://doi.org/10.38059/biodiversity.1090549

Öz

Nanoteknoloji, yaygın uygulamaları nedeniyle son zamanlarda büyük ilgi görmektedir. Tıbbi bitkiler kullanılarak gümüş nanoparçacıkların sentezi çevre dostu, düşük maliyetli ve kolaydır. Dittrichia graveolens yaprakları kullanılarak gümüş nanopartiküller (i-AgNPs) sentezlendi. i-AgNPs yapıları kapsamlı spektroskopik çalışmalarla aydınlatıldı. DPPH•, ABTS•+, and FRAP yöntemleri kullanılarak, ekstrakt ve i-AgNP’lerin antioksidan etkileri belirlendi. 3262 cm-1 de hidroksil grubunun karakteristik titreşimi FTIR spektroskopik çalışma ile belirlendi. UV-Vis spektrometresi, i-AgNPs’lerin maksimum absorpsiyonu 451 nm de gösterdi. Taramalı electron mikroskopu ile (SEM) nanoyapının büyüklüğü 30.7 nm olarak belirlendi. X ışınları kırınımı (XRD) ile nanopartikülün kristal yapısı yüzey merkezli küpik olarak belirlendi. i-AgNPs’in DPPH aktivitesi (13.4±0.34 µg/mL, IC50) ekstrakttan (15.4±0.17 µg/mL, IC50) daha yüksek bulundu. Dittrichia graveolens, indirgeyici ve stabilize edici özelliklerini ortaya çıkaran biyoaktif bileşikleri içerir. Ekstrakt ve i-AgNP’ler, gıda ve farmasötik uygulamalar için ham madde olabilecek umut verici antioksidan etki gösterdi.

Kaynakça

  • Abdel-Aziz MS, Shaheen MS, El-Nekeety AA, Abdel-Wahhab MA (2014). Antioxidant and antibacterial activity of silver nanoparticles biosynthesized using Chenopodium murale leaf extract. Journal of Saudi Chemical Society 18(4): 356-363. https://doi.org/10.1016/j.jscs.2013.09.011
  • Akalın E, Gürdal B, Olcay B (2020). General overview on the conservation of medicinal plants in Turkey. Turkish Journal of Biodiversity 3(2): 86-94. https://doi.org/10.38059/biodiversity.726745
  • Akintelu SA, Olugbeko SC, Folorunso AS (2020). A review on synthesis, optimization, characterization and antibacterial application of gold nanoparticles synthesized from plants. International Nano Letters 10(4): 237-248. https://doi.org/10.1007/s40089-020-00317-7
  • Asad M, Khan A, Jahan B (2020). Variation in biomass production of sunflower (Helianthus annuus) plants under the influence of lemongrass (Cymbopogon erectus) extract. Turkish Journal of Biodiversity 3(2): 69-75. https://doi.org/10.38059/biodiversity.729081
  • Bordoloi M, Sahoo RK, Tamuli KJ, Saikia S, Dutta PP (2020). Plant Extracts Promoted Preparation of Silver and Gold Nanoparticles: A Systematic Review. Nano 15(02): 2030001. https://doi.org/10.1142/S1793292020300017
  • Burlacu E, Tanase C, Coman N-A, Berta L (2019). A review of bark-extract-mediated green synthesis of metallic nanoparticles and their applications. Molecules 24(23): 4354. https://doi.org/10.3390/molecules24234354
  • Dede E, Genc N, Elmastas M, Aksit H, Erenler R (2019). Chemical constituents isolated from Rhododendron ungernii with antioxidant profile. The Natural Products Journal 9(3): 238-243. https://doi.org/10.2174/2210315508666181024114812
  • Elmastas M, Celik SM, Genc N, Aksit H, Erenler R, Gulcin İ (2018). Antioxidant activity of an anatolian herbal tea—Origanum minutiflorum: isolation and characterization of its secondary metabolites. International Journal of Food Properties 21(1): 374-384. https://doi.org/10.1080/10942912.2017.1416399
  • Elmastas M, Telci İ, Akşit H, Erenler R (2015). Comparison of total phenolic contents and antioxidant capacities in mint genotypes used as spices. Turkish Journal of Biochemistry 40(6): 456-462. https://doi.org/10.1515/tjb-2015-0034
  • Emi̇nagaoglu O, Ozcan M, BAK FE, Yüksel E, Beğen HA (2020). Morphological, anatomical and micromorphological characterization of Rhamnus microcarpa (Rhamnaceae). Turkish Journal of Biodiversity 3(1): 1-8. https://doi.org/10.38059/biodiversity.620587
  • Erenler R, Adak T, Karan T, Elmastas M, Yildiz I, Aksit H, Topcu G, Sanda MA (2017a). Chemical constituents isolated from Origanum solymicum with antioxidant activities. The Eurasia Proceedings of Science Technology Engineering and Mathematics 1: 139-145.
  • Erenler R, Dag B (2021). Biosynthesis of silver nanoparticles using Origanum majorana L. and evaluation of their antioxidant activity. Inorganic and Nano-Metal Chemistry 52(4): 485.492. https://doi.org/10.1080/24701556.2021.1952263
  • Erenler R, Meral B, Sen O, Elmastas M, Aydin A, Eminagaoglu O, Topcu G (2017b). Bioassay-guided isolation, identification of compounds from Origanum rotundifolium and investigation of their antiproliferative and antioxidant activities. Pharmaceutical Biology 55(1): 1646-1653. https://doi.org/10.1080/13880209.2017.1310906
  • Erenler R, Nusret G, Elmastaş M, Eminagaoglu O (2019). Evaluation of antioxidant capacity with total phenolic content of Galanthus krasnovii (Amaryllidaceae). Turkish Journal of Biodiversity 2(1): 13-17 https://doi.org/10.38059/biodiversity.526833
  • Erenler R, Sen O, Aksit H, Demirtas I, Yaglioglu AS, Elmastas M, Telci I (2016). Isolation and identification of chemical constituents from Origanum majorana and investigation of antiproliferative and antioxidant activities. Journal of the Science of Food and Agriculture 96(3): 822-836. https://doi.org/10.1002/jsfa.7155.
  • Erenler R, Telci I, Ulutas M, Demirtas I, Gul F, Elmastas M, Kayir O (2015). Chemical constituents, quantitative analysis and antioxidant activities of Echinacea purpurea (L.) moench and Echinacea pallida (N utt.) N utt. Journal of Food Biochemistry, 39(5): 622-630. https://doi.org/10.1111/jfbc.12168
  • Erenler R, Yilmaz S, Aksit H, Sen O, Genc N, Elmastas M, Demirtas I (2014). Antioxidant activities of chemical constituents isolated from Echinops orientalis Trauv. Records of Natural Products 8(1): 32-36. Gecer EN, Erenler R, Temiz C, Genc N, Yildiz I (2021). Green synthesis of silver nanoparticles from Echinacea purpurea (L.) Moench with antioxidant profile. Particulate Science and Technology 1-8. https://doi.org/10.1080/02726351.2021.1904309
  • Genc N, Yildiz I, Chaoui R, Erenler R, Temiz C, Elmastas M (2020). Biosynthesis, characterization and antioxidant activity of oleuropein-mediated silver nanoparticles. Inorganic and Nano-Metal Chemistry 51: 411-419. https://doi.org/10.1080/24701556.2020.1792495
  • Genc N, Yildiz I, Karan T, Eminagaoglu O, Erenler R (2019). Antioxidant activity and total phenolic contents of Galanthus woronowii (Amaryllidaceae). Turkish Journal of Biodiversity 2(1): 1-5.
  • Guzel A, Aksit H, Elmastas M, Erenler R (2017). Bioassay-guided isolation and identification of antioxidant flavonoids from Cyclotrichium origanifolium (Labill.) Manden. and Scheng. Pharmacognosy Magazine 13(50): 316-320. https://doi.org/10.4103/0973-1296.204556
  • Karan T, Erenler R, Bozer BM (2022). Synthesis and characterization of silver nanoparticles using curcumin: cytotoxic, apoptotic, and necrotic effects on various cell lines. Zeitschrift für Naturforschung C https://doi.org/10.1515/znc-2021-0298.
  • Kaya G, Karakaya R, Tilgel E, Sandikci M, Yucel E, Cicek G, Kayir O, Aksit H, Telci I, Guzel A, Elmastas M, Erenler R (2014). Essential oil constituents of Thuja orientalis berries. Journal of New Results in Science 7(7): 1-6.
  • Kumari R, Saini AK, Kumar A, Saini RV (2020). Apoptosis induction in lung and prostate cancer cells through silver nanoparticles synthesized from Pinus roxburghii bioactive fraction. Journal of Biological Inorganic Chemistry 25: 23-37. https://doi.org/10.1007/s00775-019-01729-3
  • Lateef A, Ojo SA, Elegbede JA (2016). The emerging roles of arthropods and their metabolites in the green synthesis of metallic nanoparticles. Nanotechnology Reviews 5(6): 601-622. https://doi.org/10.1515/ntrev-2016-0049
  • Mittal AK, Bhaumik J, Kumar S, Banerjee UC (2014). Biosynthesis of silver nanoparticles: elucidation of prospective mechanism and therapeutic potential. Journal of Colloid and Interface Science 415: 39-47. https://doi.org/10.1016/j.jcis.2013.10.018
  • Palasoglu B, Eminagaoglu O (2022). Folk medicines of Beşpare villages (Artvin-Turkey). Turkish Journal of Biodiversity 5(1): 1-16. https://doi.org/10.38059/biodiversity.1052372
  • Sahin Yaglioglu A, Akdulum B, Erenler R, Demirtas I, Telci I, Tekin S (2013). Antiproliferative activity of pentadeca-(8E, 13Z) dien-11-yn-2-one and (E)-1,8-pentadecadiene from Echinacea pallida (N utt.) N utt. roots. Medicinal Chemistry Research 22(6): 2946-2953. https://doi.org/10.1007/s00044-012-0297-2
  • Topcu G, Erenler R, Cakmak O, Johansson CB, Celik C, Chai H-B, Pezzuto JM (1999). Diterpenes from the berries of Juniperus excelsa. Phytochemistry 50(7): 1195-1199. https://doi.org/10.1016/S0031-9422(98)00675-X

Ayrıntılar

Birincil Dil İngilizce
Konular Biyoteknoloji
Bölüm Araştırma Makaleleri
Yazarlar

Esma Nur GEÇER>
TOKAT GAZİOSMANPAŞA ÜNİVERSİTESİ
0000-0002-0095-079X
Türkiye


Ramazan ERENLER> (Sorumlu Yazar)
Gaziosmanpasa University
0000-0002-0505-3190
Türkiye

Yayımlanma Tarihi 31 Mart 2022
Başvuru Tarihi 20 Mart 2022
Kabul Tarihi 31 Mart 2022
Yayınlandığı Sayı Yıl 2022, Cilt 5, Sayı 1

Kaynak Göster

APA Geçer, E. N. & Erenler, R. (2022). Biosynthesis of silver nanoparticles using Dittrichia graveolens (Asteraceae) leaves extract: characterisation and assessment of their antioxidant activity . Turkish Journal of Biodiversity , 5 (1) , 50-56 . DOI: 10.38059/biodiversity.1090549

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